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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSF
All Species:
20.3
Human Site:
S739
Identified Species:
31.9
UniProt:
P46459
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46459
NP_006169.2
744
82594
S739
L
L
R
E
E
G
A
S
P
L
D
F
D
_
_
Chimpanzee
Pan troglodytes
XP_511626
842
92301
S812
L
L
R
E
E
G
A
S
E
R
P
S
K
E
V
Rhesus Macaque
Macaca mulatta
XP_001105450
854
93325
S849
L
L
R
E
E
G
A
S
P
L
D
F
D
_
_
Dog
Lupus familis
XP_548044
752
83541
S739
L
L
R
E
E
G
A
S
P
L
D
F
E
N
G
Cat
Felis silvestris
Mouse
Mus musculus
P46460
744
82595
S739
L
M
R
E
E
G
A
S
P
L
D
F
D
_
_
Rat
Rattus norvegicus
Q9QUL6
744
82634
S739
L
M
R
E
E
G
A
S
P
L
D
F
D
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418094
740
82158
L733
V
K
K
F
L
A
L
L
R
E
E
G
T
V
P
Frog
Xenopus laevis
P23787
805
89193
G767
Q
T
L
Q
Q
S
R
G
F
G
S
F
R
F
P
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
G767
Q
T
L
Q
Q
S
R
G
F
G
S
F
R
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46461
745
82537
L739
K
M
E
E
E
G
G
L
D
M
V
A
R
Q
_
Honey Bee
Apis mellifera
XP_001120201
743
82591
L736
I
V
K
F
L
L
E
L
E
G
E
G
A
L
E
Nematode Worm
Caenorhab. elegans
Q94392
824
91316
A819
L
N
M
M
E
G
L
A
L
N
L
Y
R
_
_
Sea Urchin
Strong. purpuratus
NP_999752
746
82671
L736
R
V
P
K
F
L
S
L
M
E
E
E
G
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0Y8
742
81469
N728
G
R
E
K
I
N
I
N
H
F
Y
D
C
L
G
Baker's Yeast
Sacchar. cerevisiae
P18759
758
84038
L753
P
V
N
E
L
V
E
L
M
T
Q
S
A
_
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
86.8
98.1
N.A.
98.1
97.8
N.A.
N.A.
93.6
26.2
25
N.A.
62.4
65.8
50.6
64.8
Protein Similarity:
100
88.2
87.1
98.8
N.A.
99.7
99.7
N.A.
N.A.
96.5
44.2
44.4
N.A.
77.7
81.1
66.2
80.5
P-Site Identity:
100
53.3
100
80
N.A.
92.3
92.3
N.A.
N.A.
0
6.6
6.6
N.A.
21.4
0
23
0
P-Site Similarity:
100
53.3
100
93.3
N.A.
100
100
N.A.
N.A.
20
20
20
N.A.
35.7
26.6
38.4
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
44.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.6
64.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
7.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
15.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
40
7
0
0
0
7
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
34
7
27
0
0
% D
% Glu:
0
0
14
54
54
0
14
0
14
14
20
7
7
7
7
% E
% Phe:
0
0
0
14
7
0
0
0
14
7
0
47
0
14
0
% F
% Gly:
7
0
0
0
0
54
7
14
0
20
0
14
7
7
14
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
7
7
14
14
0
0
0
0
0
0
0
0
7
0
0
% K
% Leu:
47
27
14
0
20
14
14
34
7
34
7
0
0
14
7
% L
% Met:
0
20
7
7
0
0
0
0
14
7
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
7
0
7
0
7
0
0
0
7
0
% N
% Pro:
7
0
7
0
0
0
0
0
34
0
7
0
0
0
20
% P
% Gln:
14
0
0
14
14
0
0
0
0
0
7
0
0
7
0
% Q
% Arg:
7
7
40
0
0
0
14
0
7
7
0
0
27
0
0
% R
% Ser:
0
0
0
0
0
14
7
40
0
0
14
14
0
0
0
% S
% Thr:
0
14
0
0
0
0
0
0
0
7
0
0
7
0
0
% T
% Val:
7
20
0
0
0
7
0
0
0
0
7
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
47
% _